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Vitamin B6 Nerve Damage: Where Do the Limits Sit, and What About SciatiEase's 20 mg?
Vitamin B6 nerve damage is a known risk of high supplement intakes, and reports exist below 500 mg a day. The US upper limit is 100 mg a day; Europe's is 12 mg. SciatiEase holds 20 mg of B6 per 4 capsules and 10 mg per 2. Stop and call a doctor if tingling, burning or numbness worsens.
Written by the SciatiEase label deskUpdated · 4 min read

The risk01
Can vitamin B6 cause nerve damage?
Vitamin B6 nerve damage happens with long, high intakes, but cases have been reported below 500 mg a day. The picture is numbness in a stocking-glove pattern, plus balance problems (NIH ODS, Vitamin B6).
Symptoms usually improve after stopping and mostly clear within 6 months. A few people do not recover (StatPearls, Vitamin B6 Toxicity).
The limits02
What is the safe upper limit for vitamin B6?
The limit depends on who sets it. The US upper limit is 100 mg a day. Europe's food safety agency set 12 mg a day in 2023 (NIH ODS, Vitamin B6).
Australia requires a warning above 10 mg a day and says risk cannot be excluded below 50 mg (TGA, Vitamin B6 rescheduling).
| Source | Figure per day |
|---|---|
| US upper limit | 100 mg |
| Europe (EFSA) | 12 mg |
| SciatiEase, 4 capsules | 20 mg |
| SciatiEase, 2 capsules | 10 mg |
The label03
Where does SciatiEase's 20 mg of B6 land?
At 4 capsules, SciatiEase's 20 mg of B6 is under the US limit and above Europe's. At 2 capsules it is 10 mg.
Tap a number to read that part of the panel.
- Serving size
4 capsules per serving, 30 servings per container: one bottle is 30 days at the label serving.
- % Daily Value
B vitamins far above 100% DV: B2 1,923%, B6 1,177%, B12 41,667%. Folate is 120%.
- Four B vitamins
B2 25 mg, B6 20 mg, folate 500 mcg DFE, B12 1 mg, all in active forms.
- AlphaPalm Blend 750 mg
R-alpha lipoic acid 250 mg plus palmitoylethanolamide (PEA) 500 mg, both amounts printed.
- Acetyl-L-carnitine
250 mg per 4 capsules. Neuropathy trials used 1,000-3,000 mg a day.
- Benfotiamine
200 mg per 4 capsules, a fat-soluble form of vitamin B1.
- Proprietary blend 50 mg
Feverfew, passionflower, Chinese skullcap and oat straw, each a 4:1 extract. Single amounts are not shown.
- Other ingredients
Gelatin capsule, microcrystalline cellulose, vegetable stearate and silica. Gelatin means not vegetarian.

SciatiEase: from $49 a bottle120 capsules · 1, 3 or 6 bottles · free US shipping on 3 or 6 · 180-day guarantee
See packsWhat to do04
What should you do about vitamin B6 intake?
Add up B6 from every pill you take. Multivitamins also carry B6. Keep taking prescribed medicine.
If tingling, burning or numbness gets worse.
Three bottles cost $177, six cost $294, with a 180-day guarantee. See the side effects guide and the ingredients.
FAQ05
Vitamin B6 questions
How long does B6 nerve damage take to appear?
Reports describe months of intake before symptoms, though timing varies by dose and person. Symptoms generally improve after stopping, so tell a doctor about every supplement.
Is the P5P form of B6 safer than pyridoxine?
We found no source showing that. Limits are set for total vitamin B6, so P5P counts toward the same totals. SciatiEase lists pyridoxal-5-phosphate.
Do multivitamins add to my B6 total?
Yes. B6 shows up in multivitamins, B-complex pills and some fortified foods, so read each label and add the milligrams before comparing with a limit.
Who wrote this06
Written and reviewed by
Pages built from the label, the official site, the sales page and linked NIH, FDA, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a SciatiEase authorized U.S. retailer, not by the manufacturer. We are paid a commission when you buy through our order links.
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