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Is a diabetic neuropathy supplement safe to add?
A diabetic neuropathy supplement comes second to glucose control, which is the key step. Studies of B vitamins, alpha-lipoic acid and benfotiamine in diabetic nerve damage are small and mixed. Some nutrients can also lower blood sugar, so tell your doctor before adding one.
Written by the SciatiEase label deskUpdated · 4 min read

First things first01
What comes before a diabetic neuropathy supplement?
Before any diabetic neuropathy supplement comes blood glucose control and daily foot checks. Peripheral neuropathy affects up to half of people with diabetes (NIDDK, Peripheral Neuropathy).
Keep taking prescribed medicine, including diabetes drugs.
Evidence02
What does research say about supplements for diabetic nerve damage?
Research on supplements for diabetic nerve damage is small and mixed. Benfotiamine showed a slight vibration-sense gain in one 8-week trial and no clear pain gain in two others (Cochrane, Vitamin B for neuropathy).
| Nutrient | What was found |
|---|---|
| Benfotiamine | 300 to 600 mg a day, mixed (BENDIP trial, benfotiamine 2008) |
| Alpha-lipoic acid | Probably little or no effect at 6 months (Cochrane, Alpha-lipoic acid 2024) |
| B vitamins | Insufficient evidence (Cochrane, Vitamin B for neuropathy) |
Medicine check03
Can a diabetic neuropathy supplement affect blood sugar?
A diabetic neuropathy supplement can affect blood sugar, since alpha-lipoic acid may lower it. It can add to diabetes medicine (MSKCC, Alpha-lipoic acid).
Answer the questions below, then call your doctor.

SciatiEase: from $49 a bottle120 capsules · 1, 3 or 6 bottles · free US shipping on 3 or 6 · 180-day guarantee
See packsIf your doctor agrees04
Where can you read a label with these nutrients?
The SciatiEase order page lists benfotiamine and alpha-lipoic acid in full. Show it to your doctor first.
Three bottles are $177 and six are $294, with a 180-day guarantee.
See the medicines guide and the side effects page.
FAQ05
Questions about diabetes and nerves
Should I check my blood sugar more often after starting a supplement?
Ask your doctor. Alpha-lipoic acid can lower blood sugar and add to diabetes drugs (MSKCC, Alpha-lipoic acid), so your doctor may want closer readings at the start.
Do diabetic foot checks replace supplements?
They do different jobs. Daily foot checks catch injuries you may not feel (NIDDK, Peripheral Neuropathy). A supplement does not do that work.
Is benfotiamine different from regular thiamin?
Benfotiamine is a fat-soluble form of vitamin B1 (NIH ODS, Thiamin (benfotiamine)). Trials in diabetic nerve damage used 300 to 600 mg a day, more than many capsules hold.
Who wrote this06
Written and reviewed by
Pages built from the label, the official site, the sales page and linked NIH, FDA, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a SciatiEase authorized U.S. retailer, not by the manufacturer. We are paid a commission when you buy through our order links.
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